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Engineered organism could diagnose Crohn’s disease flareups – Newswise

In an important step toward the clinical application of synthetic biology, Rice University researchers have engineered a bacterium with the necessary capabiliti

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Newswise — HOUSTON – (May 17, 2021) – In an important step toward the clinical application of synthetic biology, Rice University researchers have engineered a bacterium with the necessary capabilities for diagnosing a human disease.
The engineered strain of the gut bacteria E. coli senses pH and glows when it encounters acidosis, an acidic condition that often occurs during flareups of inflammatory bowel diseases like colitis, ileitis and Crohn’s disease.
Researchers at the University of Colorado…

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